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High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation
BACKGROUND: By post-transcriptionally regulating multiple target transcripts, microRNAs (miRNAs or miR) play important biological functions. H1 embryonic stem cells (hESCs) and NTera-2 embryonal carcinoma cells (ECCs) are two of the most widely used human pluripotent model cell lines, sharing severa...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615276/ https://www.ncbi.nlm.nih.gov/pubmed/31287022 http://dx.doi.org/10.1186/s13287-019-1318-6 |