High-content screen in human pluripotent cells identifies miRNA-regulated pathways controlling pluripotency and differentiation

BACKGROUND: By post-transcriptionally regulating multiple target transcripts, microRNAs (miRNAs or miR) play important biological functions. H1 embryonic stem cells (hESCs) and NTera-2 embryonal carcinoma cells (ECCs) are two of the most widely used human pluripotent model cell lines, sharing severa...

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Detalles Bibliográficos
Autores principales: de Souza Lima, Ildercílio Mota, Schiavinato, Josiane Lilian dos Santos, Paulino Leite, Sarah Blima, Sastre, Danuta, Bezerra, Hudson Lenormando de Oliveira, Sangiorgi, Bruno, Corveloni, Amanda Cristina, Thomé, Carolina Hassibe, Faça, Vitor Marcel, Covas, Dimas Tadeu, Zago, Marco Antônio, Giacca, Mauro, Mano, Miguel, Panepucci, Rodrigo Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615276/
https://www.ncbi.nlm.nih.gov/pubmed/31287022
http://dx.doi.org/10.1186/s13287-019-1318-6

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