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Population pharmacokinetics of intravenous sufentanil in critically ill patients supported with extracorporeal membrane oxygenation therapy

BACKGROUND: Sufentanil is commonly used for analgesia and sedation during extracorporeal membrane oxygenation (ECMO). Both ECMO and the pathophysiological changes derived from critical illness have significant effects on the pharmacokinetics (PK) of drugs, yet reports of ECMO and sufentanil PK are s...

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Detalles Bibliográficos
Autores principales: Hahn, Jongsung, Yang, Seungwon, Min, Kyoung Lok, Kim, Dasohm, Jin, Byung Hak, Park, Changhun, Park, Min Soo, Wi, Jin, Chang, Min Jung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615282/
https://www.ncbi.nlm.nih.gov/pubmed/31288863
http://dx.doi.org/10.1186/s13054-019-2508-4