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Chondrogenic induction of human osteoarthritic cartilage-derived mesenchymal stem cells activates mineralization and hypertrophic and osteogenic gene expression through a mechanomiR

BACKGROUND: While bone marrow-derived mesenchymal stem cells (BMSC) are established sources for stem cell-based cartilage repair therapy, articular cartilage-derived mesenchymal stem cells from osteoarthritis patients (OA-MSC) are new and potentially attractive candidates. We compared OA-MSC and BMS...

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Detalles Bibliográficos
Autores principales: Hu, Nan, Gao, Yun, Jayasuriya, Chathuraka T., Liu, Wenguang, Du, Heng, Ding, Jing, Feng, Meng, Chen, Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615283/
https://www.ncbi.nlm.nih.gov/pubmed/31287025
http://dx.doi.org/10.1186/s13075-019-1949-0