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Protocatechuic acid improved growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers

The aim of this study was to investigate the effect of protocatechuic acid (PCA) on the growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers. Growing broilers were fed the basal diet or diets supplemented with 300 or 600 mg/kg PCA, or 200 mg/kg enramycin for 5...

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Autores principales: Wang, Yibing, Wang, Yuanyuan, Wang, Baikui, Mei, Xiaoqiang, Jiang, Shouqun, Li, Weifen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Poultry Science Association, Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615542/
https://www.ncbi.nlm.nih.gov/pubmed/30938807
http://dx.doi.org/10.3382/ps/pez124
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author Wang, Yibing
Wang, Yuanyuan
Wang, Baikui
Mei, Xiaoqiang
Jiang, Shouqun
Li, Weifen
author_facet Wang, Yibing
Wang, Yuanyuan
Wang, Baikui
Mei, Xiaoqiang
Jiang, Shouqun
Li, Weifen
author_sort Wang, Yibing
collection PubMed
description The aim of this study was to investigate the effect of protocatechuic acid (PCA) on the growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers. Growing broilers were fed the basal diet or diets supplemented with 300 or 600 mg/kg PCA, or 200 mg/kg enramycin for 52 D. We found that addition of 300 mg/kg PCA significantly increased body weight, live weight, and carcass weight and decreased the feed to gain ratio of broilers; PCA improved meat quality through reducing shear force, and increasing a* (relative redness) and decreasing b* (relative yellowness) at 24 h after slaughter. The activities of alkaline phosphatase and diamine oxidase in plasma were significantly decreased by administration of 300 mg/kg PCA; PCA also significantly increased total antioxidant capability and decreased malondialdehyde content and activity of xanthine oxidase in liver. Meanwhile, it enhanced activities of total superoxide dismutase, glutathione s-transferase, and glutathione peroxidase in the jejunal mucosa. Interleukin-10 and transforming growth factor-β were significantly increased in jejunal mucosa and plasma of 300 mg/kg PCA diet group, whereas interluekin-2 and interferon-γ dropped dramatically. Moreover, relative expression of apoptosis-related genes decreased in liver, whereas that of intestinal barrier-related and immunity-related genes increased in jejunum. Furthermore, 300 mg/kg PCA treatment significantly changed α-diversity and structure of the cecal microflora in broilers, with increasing relative abundance of Firmicutes and Actinobacteria while reducing Bacteroidetes and Proteobacteria. These results indicated that PCA improved the feed efficiency, growth performance, meat quality of broilers, and antioxidant capacity. It also enhanced intestinal immune function and improved the structure of intestinal flora to favor improved intestinal health in Chinese yellow-feathered broilers.
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spelling pubmed-66155422019-07-12 Protocatechuic acid improved growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers Wang, Yibing Wang, Yuanyuan Wang, Baikui Mei, Xiaoqiang Jiang, Shouqun Li, Weifen Poult Sci Immunology, Health and Disease The aim of this study was to investigate the effect of protocatechuic acid (PCA) on the growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers. Growing broilers were fed the basal diet or diets supplemented with 300 or 600 mg/kg PCA, or 200 mg/kg enramycin for 52 D. We found that addition of 300 mg/kg PCA significantly increased body weight, live weight, and carcass weight and decreased the feed to gain ratio of broilers; PCA improved meat quality through reducing shear force, and increasing a* (relative redness) and decreasing b* (relative yellowness) at 24 h after slaughter. The activities of alkaline phosphatase and diamine oxidase in plasma were significantly decreased by administration of 300 mg/kg PCA; PCA also significantly increased total antioxidant capability and decreased malondialdehyde content and activity of xanthine oxidase in liver. Meanwhile, it enhanced activities of total superoxide dismutase, glutathione s-transferase, and glutathione peroxidase in the jejunal mucosa. Interleukin-10 and transforming growth factor-β were significantly increased in jejunal mucosa and plasma of 300 mg/kg PCA diet group, whereas interluekin-2 and interferon-γ dropped dramatically. Moreover, relative expression of apoptosis-related genes decreased in liver, whereas that of intestinal barrier-related and immunity-related genes increased in jejunum. Furthermore, 300 mg/kg PCA treatment significantly changed α-diversity and structure of the cecal microflora in broilers, with increasing relative abundance of Firmicutes and Actinobacteria while reducing Bacteroidetes and Proteobacteria. These results indicated that PCA improved the feed efficiency, growth performance, meat quality of broilers, and antioxidant capacity. It also enhanced intestinal immune function and improved the structure of intestinal flora to favor improved intestinal health in Chinese yellow-feathered broilers. Poultry Science Association, Inc. 2019-08 2019-04-02 /pmc/articles/PMC6615542/ /pubmed/30938807 http://dx.doi.org/10.3382/ps/pez124 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of Poultry Science Association. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Immunology, Health and Disease
Wang, Yibing
Wang, Yuanyuan
Wang, Baikui
Mei, Xiaoqiang
Jiang, Shouqun
Li, Weifen
Protocatechuic acid improved growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers
title Protocatechuic acid improved growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers
title_full Protocatechuic acid improved growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers
title_fullStr Protocatechuic acid improved growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers
title_full_unstemmed Protocatechuic acid improved growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers
title_short Protocatechuic acid improved growth performance, meat quality, and intestinal health of Chinese yellow-feathered broilers
title_sort protocatechuic acid improved growth performance, meat quality, and intestinal health of chinese yellow-feathered broilers
topic Immunology, Health and Disease
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615542/
https://www.ncbi.nlm.nih.gov/pubmed/30938807
http://dx.doi.org/10.3382/ps/pez124
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