Metabolic requirements of human pro-inflammatory B cells in aging and obesity

The subset of pro-inflammatory B cells, called late memory, tissue-like or double negative (DN), accumulates in the blood of elderly individuals. Here we show that DN B cells do not proliferate and do not make antibodies to influenza antigens, but they secrete antibodies with autoimmune reactivity,...

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Detalles Bibliográficos
Autores principales: Frasca, Daniela, Diaz, Alain, Romero, Maria, Thaller, Seth, Blomberg, Bonnie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615614/
https://www.ncbi.nlm.nih.gov/pubmed/31287846
http://dx.doi.org/10.1371/journal.pone.0219545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615614/
https://www.ncbi.nlm.nih.gov/pubmed/31287846
http://dx.doi.org/10.1371/journal.pone.0219545

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