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Unified single-cell analysis of testis gene regulation and pathology in five mouse strains

To fully exploit the potential of single-cell functional genomics in the study of development and disease, robust methods are needed to simplify the analysis of data across samples, time-points and individuals. Here we introduce a model-based factor analysis method, SDA, to analyze a novel 57,600 ce...

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Detalles Bibliográficos
Autores principales: Jung, Min, Wells, Daniel, Rusch, Jannette, Ahmad, Suhaira, Marchini, Jonathan, Myers, Simon R, Conrad, Donald F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615865/
https://www.ncbi.nlm.nih.gov/pubmed/31237565
http://dx.doi.org/10.7554/eLife.43966