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wPrognostic significance of VHL, HIF1A, HIF2A, VEGFA and p53 expression in patients with clear-cell renal cell carcinoma treated with sunitinib as first-line treatment

Clear cell renal cell carcinoma (ccRCC) is the most common subtype of renal cell cancer, characterized by the highest mortality rate among other RCC subtypes due to the occurrence of metastasis and drug resistance following surgery. The Von Hippel-Lindau tumor suppressor (VHL)-hypoxia-inducible fact...

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Detalles Bibliográficos
Autores principales: Wierzbicki, Piotr M., Klacz, Jakub, Kotulak-Chrzaszcz, Anna, Wronska, Agata, Stanislawowski, Marcin, Rybarczyk, Agnieszka, Ludziejewska, Aleksandra, Kmiec, Zbigniew, Matuszewski, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615924/
https://www.ncbi.nlm.nih.gov/pubmed/31268155
http://dx.doi.org/10.3892/ijo.2019.4830