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Molecular profiling of the tumor microenvironment in glioblastoma patients: correlation of microglia/macrophage polarization state with metalloprotease expression profiles and survival

Due to poor prognosis of glioblastoma (GBM), there is an urgent need to develop new therapeutic strategies. Besides eliminating GBM tumor cells and stem cells, a novel therapeutic approach aims to target Glioma-associated microglia/macrophages (GAMs). We investigated the molecular profile of GAMs co...

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Detalles Bibliográficos
Autores principales: Gjorgjevski, Marko, Hannen, Ricarda, Carl, Barbara, Li, Yu, Landmann, Emilie, Buchholz, Malte, Bartsch, Jörg W., Nimsky, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616040/
https://www.ncbi.nlm.nih.gov/pubmed/31142630
http://dx.doi.org/10.1042/BSR20182361