Cargando…
Molecular profiling of the tumor microenvironment in glioblastoma patients: correlation of microglia/macrophage polarization state with metalloprotease expression profiles and survival
Due to poor prognosis of glioblastoma (GBM), there is an urgent need to develop new therapeutic strategies. Besides eliminating GBM tumor cells and stem cells, a novel therapeutic approach aims to target Glioma-associated microglia/macrophages (GAMs). We investigated the molecular profile of GAMs co...
Autores principales: | Gjorgjevski, Marko, Hannen, Ricarda, Carl, Barbara, Li, Yu, Landmann, Emilie, Buchholz, Malte, Bartsch, Jörg W., Nimsky, Christopher |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Portland Press Ltd.
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616040/ https://www.ncbi.nlm.nih.gov/pubmed/31142630 http://dx.doi.org/10.1042/BSR20182361 |
Ejemplares similares
-
The Metalloprotease-Disintegrin ADAM8 Alters the Tumor Suppressor miR-181a-5p Expression Profile in Glioblastoma Thereby Contributing to Its Aggressiveness
por: Schäfer, Agnes, et al.
Publicado: (2022) -
Profiling of metalloprotease activities in cerebrospinal fluids of patients with neoplastic meningitis
por: Conrad, Catharina, et al.
Publicado: (2017) -
Comparative Transcriptomic Analysis of Temozolomide Resistant Primary GBM Stem-Like Cells and Recurrent GBM Identifies Up-Regulation of the Carbonic Anhydrase CA2 Gene as Resistance Factor
por: Hannen, Ricarda, et al.
Publicado: (2019) -
Macrophages/Microglia in the Glioblastoma Tumor Microenvironment
por: Ma, Jun, et al.
Publicado: (2021) -
Lactate modulates microglia polarization via IGFBP6 expression and remodels tumor microenvironment in glioblastoma
por: Longhitano, Lucia, et al.
Publicado: (2022)