From Synthetic Fragments of Endogenous Three-Finger Proteins to Potential Drugs

The proteins of the Ly6 family have a three-finger folding as snake venom α-neurotoxins, targeting nicotinic acetylcholine receptors (nAChRs), and some of them, like mammalian secreted Ly6/uPAR protein (SLURP1) and membrane-attached Ly-6/neurotoxin (Lynx1), also interact with distinct nAChR subtypes...

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Detalles Bibliográficos
Autores principales: Kryukova, Elena V., Egorova, Natalia S., Kudryavtsev, Denis S., Lebedev, Dmitry S., Spirova, Ekaterina N., Zhmak, Maxim N., Garifulina, Aleksandra I., Kasheverov, Igor E., Utkin, Yuri N., Tsetlin, Victor I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616073/
https://www.ncbi.nlm.nih.gov/pubmed/31333465
http://dx.doi.org/10.3389/fphar.2019.00748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616073/
https://www.ncbi.nlm.nih.gov/pubmed/31333465
http://dx.doi.org/10.3389/fphar.2019.00748

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