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Protein O-Fucosyltransferase 2 Is Not Essential for Plasmodium berghei Development

Thrombospondin type I repeat (TSR) domains are commonly O-fucosylated by protein O-fucosyltransferase 2 (PoFUT2), and this modification is required for optimal folding and secretion of TSR-containing proteins. The human malaria parasite Plasmodium falciparum expresses proteins containing TSR domains...

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Detalles Bibliográficos
Autores principales: Sanz, Silvia, Aquilini, Eleonora, Tweedell, Rebecca E., Verma, Garima, Hamerly, Timothy, Hritzo, Bernadette, Tripathi, Abhai, Machado, Marta, Churcher, Thomas S., Rodrigues, João A., Izquierdo, Luis, Dinglasan, Rhoel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616114/
https://www.ncbi.nlm.nih.gov/pubmed/31334132
http://dx.doi.org/10.3389/fcimb.2019.00238