Ruthenium Complexes With Piplartine Cause Apoptosis Through MAPK Signaling by a p53-Dependent Pathway in Human Colon Carcinoma Cells and Inhibit Tumor Development in a Xenograft Model

Ruthenium complexes with piplartine, [Ru(piplartine)(dppf)(bipy)](PF(6))(2) (1) and [Ru(piplartine)(dppb)(bipy)](PF(6))(2) (2) (dppf = 1,1-bis(diphenylphosphino) ferrocene; dppb = 1,4-bis(diphenylphosphino)butane and bipy = 2,2′-bipyridine), were recently synthesized and displayed more potent cytoto...

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Detalles Bibliográficos
Autores principales: Baliza, Ingrid R. S., Silva, Suellen L. R., Santos, Luciano de S., Neto, João H. Araujo, Dias, Rosane B., Sales, Caroline B. S., Rocha, Clarissa A. Gurgel, Soares, Milena B. P., Batista, Alzir A., Bezerra, Daniel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616125/
https://www.ncbi.nlm.nih.gov/pubmed/31334116
http://dx.doi.org/10.3389/fonc.2019.00582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616125/
https://www.ncbi.nlm.nih.gov/pubmed/31334116
http://dx.doi.org/10.3389/fonc.2019.00582

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