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Impaired l-arginine metabolism marks endothelial dysfunction in CD73-deficient mice

Changes in the ecto-5′-nucleotidase activity—an extracellular nucleotide catabolic enzyme may lead to the inflammation and endothelial dysfunction. We investigated the effect of CD73 deletion on the endothelial function and l-arginine metabolism in various age groups of mice. 1-,3-,6-, and 12-month-...

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Detalles Bibliográficos
Autores principales: Mierzejewska, P., Zabielska, M. A., Kutryb-Zajac, B., Tomczyk, M., Koszalka, P., Smolenski, R. T., Slominska, E. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616215/
https://www.ncbi.nlm.nih.gov/pubmed/31093850
http://dx.doi.org/10.1007/s11010-019-03537-4