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A large-scale analysis of targeted metabolomics data from heterogeneous biological samples provides insights into metabolite dynamics

INTRODUCTION: We previously developed a tandem mass spectrometry-based label-free targeted metabolomics analysis framework coupled to two distinct chromatographic methods, reversed-phase liquid chromatography (RPLC) and hydrophilic interaction liquid chromatography (HILIC), with dynamic multiple rea...

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Detalles Bibliográficos
Autores principales: Lee, Ho-Joon, Kremer, Daniel M., Sajjakulnukit, Peter, Zhang, Li, Lyssiotis, Costas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616221/
https://www.ncbi.nlm.nih.gov/pubmed/31289941
http://dx.doi.org/10.1007/s11306-019-1564-8