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Co-treatment with interferon-γ and 1-methyl tryptophan ameliorates cardiac fibrosis through cardiac myofibroblasts apoptosis

Cardiac remodeling characterized by cardiac fibrosis is a pathologic process occurring after acute myocardial infarction. Fibrosis can be ameliorated by interferon-gamma (IFN-γ), which is a soluble cytokine showing various effects such as anti-fibrosis, apoptosis, anti-proliferation, immunomodulatio...

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Detalles Bibliográficos
Autores principales: Lee, Jun-Won, Oh, Ji Eun, Rhee, Ki-Jong, Yoo, Byung-Su, Eom, Young Woo, Park, Sang Wook, Lee, Ji Hyun, Son, Jung-Woo, Youn, Young Jin, Ahn, Min-Soo, Ahn, Sung-Gyun, Kim, Jang-Young, Lee, Seung-Hwan, Yoon, Junghan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616223/
https://www.ncbi.nlm.nih.gov/pubmed/31006829
http://dx.doi.org/10.1007/s11010-019-03542-7