Cell-Free Co-Translational Approaches for Producing Mammalian Receptors: Expanding the Cell-Free Expression Toolbox Using Nanolipoproteins

Membranes proteins make up more than 60% of current drug targets and account for approximately 30% or more of the cellular proteome. Access to this important class of proteins has been difficult due to their inherent insolubility and tendency to aggregate in aqueous solutions. Understanding membrane...

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Detalles Bibliográficos
Autores principales: Shelby, Megan L., He, Wei, Dang, Amanda T., Kuhl, Tonya L., Coleman, Matthew A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616253/
https://www.ncbi.nlm.nih.gov/pubmed/31333463
http://dx.doi.org/10.3389/fphar.2019.00744

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616253/
https://www.ncbi.nlm.nih.gov/pubmed/31333463
http://dx.doi.org/10.3389/fphar.2019.00744

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