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Reconstitution of Microtubule Nucleation In Vitro Reveals Novel Roles for Mzt1

Microtubule (MT) nucleation depends on the γ-tubulin complex (γ-TuC), in which multiple copies of the heterotetrameric γ-tubulin small complex (γ-TuSC) associate to form a ring-like structure (in metazoans, γ-tubulin ring complex; γ-TuRC) [1, 2, 3, 4, 5, 6, 7]. Additional conserved regulators of the...

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Detalles Bibliográficos
Autores principales: Leong, Su Ling, Lynch, Eric M., Zou, Juan, Tay, Ye Dee, Borek, Weronika E., Tuijtel, Maarten W., Rappsilber, Juri, Sawin, Kenneth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616311/
https://www.ncbi.nlm.nih.gov/pubmed/31287970
http://dx.doi.org/10.1016/j.cub.2019.05.058