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Safety of anti-VEGF treatments in a diabetic rat model and retinal cell culture

PURPOSE: To analyze the safety of different concentrations of anti-VEGF on retinal cells. METHODS: Non-diabetic and streptozotocin (STZ)-induced diabetic rats received intravitreal rat anti-VEGF injections that had final vitreous concentrations of 0, 0.0625, 0.125 (clinical dose), and 0.25 mg/mL. Ra...

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Detalles Bibliográficos
Autores principales: Filek, Richard, Hooper, Phil, Sheidow, Tom G, Liu, Hong, Chakrabarti, Subrata, Hutnik, Cindy ML
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616316/
https://www.ncbi.nlm.nih.gov/pubmed/31308619
http://dx.doi.org/10.2147/OPTH.S199771