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How Gastrin-Releasing Peptide Opens the Spinal Gate for Itch
Spinal transmission of pruritoceptive (itch) signals requires transneuronal signaling by gastrin-releasing peptide (GRP) produced by a subpopulation of dorsal horn excitatory interneurons. These neurons also express the glutamatergic marker vGluT2, raising the question of why glutamate alone is insu...
Autores principales: | Pagani, Martina, Albisetti, Gioele W., Sivakumar, Nandhini, Wildner, Hendrik, Santello, Mirko, Johannssen, Helge C., Zeilhofer, Hanns Ulrich |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616317/ https://www.ncbi.nlm.nih.gov/pubmed/31103358 http://dx.doi.org/10.1016/j.neuron.2019.04.022 |
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