Integrin α7 expression is increased in asthmatic patients and its inhibition reduces Kras protein abundance in airway smooth muscle cells

Airway smooth muscle (ASM) cells exhibit plastic phenotypic behavior marked by reversible modulation and maturation between contractile and proliferative phenotypic states. Integrins are a class of transmembrane proteins that have been implicated as novel therapeutic targets for asthma treatment. We...

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Detalles Bibliográficos
Autores principales: Teoh, Chun Ming, Tan, Sheryl S. L., Langenbach, Shenna Y., Wong, Amanda H., Cheong, Dorothy H. J., Tam, John K. C., New, Chih Sheng, Tran, Thai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616330/
https://www.ncbi.nlm.nih.gov/pubmed/31289310
http://dx.doi.org/10.1038/s41598-019-46260-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616330/
https://www.ncbi.nlm.nih.gov/pubmed/31289310
http://dx.doi.org/10.1038/s41598-019-46260-2

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