Cargando…

Endothelin-1-Induced Microvascular ROS and Contractility in Angiotensin-II-Infused Mice Depend on COX and TP Receptors

(1) Background: Angiotensin II (Ang II) and endothelin 1 (ET-1) generate reactive oxygen species (ROS) that can activate cyclooxygenase (COX). However, thromboxane prostanoid receptors (TPRs) are required to increase systemic markers of ROS during Ang II infusion in mice. We hypothesized that COX an...

Descripción completa

Detalles Bibliográficos
Autores principales: Wilcox, Christopher S., Wang, Cheng, Wang, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616505/
https://www.ncbi.nlm.nih.gov/pubmed/31234522
http://dx.doi.org/10.3390/antiox8060193