Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport

In vitro models of the small intestine are crucial tools for the prediction of drug absorption. The Caco-2 monolayer transwell model has been widely employed to assess drug absorption across the intestine. However, it is now well-established that 3D in vitro models capture tissue-specific architectu...

Descripción completa

Detalles Bibliográficos
Autores principales: Samy, Karen E., Levy, Elizabeth S., Phong, Kiet, Demaree, Benjamin, Abate, Adam R., Desai, Tejal A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616551/
https://www.ncbi.nlm.nih.gov/pubmed/31289365
http://dx.doi.org/10.1038/s41598-019-46408-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616551/
https://www.ncbi.nlm.nih.gov/pubmed/31289365
http://dx.doi.org/10.1038/s41598-019-46408-0

Ejemplares similares