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Human intestinal spheroids cultured using Sacrificial Micromolding as a model system for studying drug transport
In vitro models of the small intestine are crucial tools for the prediction of drug absorption. The Caco-2 monolayer transwell model has been widely employed to assess drug absorption across the intestine. However, it is now well-established that 3D in vitro models capture tissue-specific architectu...
Autores principales: | Samy, Karen E., Levy, Elizabeth S., Phong, Kiet, Demaree, Benjamin, Abate, Adam R., Desai, Tejal A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616551/ https://www.ncbi.nlm.nih.gov/pubmed/31289365 http://dx.doi.org/10.1038/s41598-019-46408-0 |
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