Use of syngeneic cells expressing membrane-bound GM-CSF as an adjuvant to induce antibodies against native multi-pass transmembrane protein

Membrane antigens (mAgs) are important targets for the development of antibody (Ab) drugs. However, native mAgs are not easily prepared, causing difficulties in acquiring functional Abs. In this study, we present a platform in which human mAgs were expressed in native form on cell adjuvants made wit...

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Detalles Bibliográficos
Autores principales: Huang, Chien-Chiao, Cheng, Kai-Wen, Hsieh, Yuan-Chin, Lin, Wen-Wei, Cheng, Chiu-Min, Yuan, Shyng-Shiou F., Chen, I-Ju, Cheng, Yi-An, Lu, Yun-Chi, Huang, Bo-Cheng, Tung, Yi-Ching, Cheng, Tian-Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616555/
https://www.ncbi.nlm.nih.gov/pubmed/31289297
http://dx.doi.org/10.1038/s41598-019-45160-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616555/
https://www.ncbi.nlm.nih.gov/pubmed/31289297
http://dx.doi.org/10.1038/s41598-019-45160-9

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