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Discovery of novel oestrogen receptor α agonists and antagonists by screening a revisited privileged structure moiety for nuclear receptors

Bisphenol A (BPA) is used as an industrial raw material for polycarbonate plastics and epoxy resins; however, various concerns have been reported regarding its status as an endocrine-disrupting chemical. BPA interacts not only with oestrogen receptors (ERs) but constitutive androstane receptor, preg...

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Detalles Bibliográficos
Autores principales: Masuya, Takahiro, Iwamoto, Masaki, Liu, Xiaohui, Matsushima, Ayami
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616570/
https://www.ncbi.nlm.nih.gov/pubmed/31289329
http://dx.doi.org/10.1038/s41598-019-46272-y