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The Pol β variant containing exon α is deficient in DNA polymerase but has full dRP lyase activity
DNA polymerase (Pol) β is a key enzyme in base excision repair (BER), an important repair system for maintaining genomic integrity. We previously reported the presence of a Pol β transcript containing exon α (105-nucleotide) in normal and colon cancer cell lines. The transcript carried an insertion...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616571/ https://www.ncbi.nlm.nih.gov/pubmed/31289286 http://dx.doi.org/10.1038/s41598-019-45846-0 |