Isoniazid Concentration and NAT2 Genotype Predict Risk of Systemic Drug Reactions during 3HP for LTBI

Weekly rifapentine and isoniazid therapy (known as 3HP) for latent tuberculosis infection (LTBI) is increasingly used, but systemic drug reactions (SDR) remain a major concern. Methods: We prospectively recruited two LTBI cohorts who received the 3HP regimen. In the single-nucleotide polymorphism (S...

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Detalles Bibliográficos
Autores principales: Lee, Meng-Rui, Huang, Hung-Ling, Lin, Shu-Wen, Cheng, Meng-Hsuan, Lin, Ya-Ting, Chang, So-Yi, Yan, Bo-Shiun, Kuo, Ching-Hua, Lu, Po-Liang, Wang, Jann-Yuan, Chong, Inn-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616849/
https://www.ncbi.nlm.nih.gov/pubmed/31174321
http://dx.doi.org/10.3390/jcm8060812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616849/
https://www.ncbi.nlm.nih.gov/pubmed/31174321
http://dx.doi.org/10.3390/jcm8060812

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