Overexpression of IL-10 Enhances the Efficacy of Human Umbilical-Cord-Derived Mesenchymal Stromal Cells in E. coli Pneumosepsis

Enhancing the immunomodulatory effects of mesenchymal stromal cells (MSCs) may increase their effects in sepsis. We tested the potential for overexpression of Interleukin-10 (IL-10) in human umbilical cord (UC) MSCs to increase MSC efficacy in Escherichia coli (E. coli) pneumosepsis and to enhance h...

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Detalles Bibliográficos
Autores principales: Jerkic, Mirjana, Masterson, Claire, Ormesher, Lindsay, Gagnon, Stéphane, Goyal, Sakshi, Rabani, Razieh, Otulakowski, Gail, Zhang, Haibo, Kavanagh, Brian P., Laffey, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616885/
https://www.ncbi.nlm.nih.gov/pubmed/31200579
http://dx.doi.org/10.3390/jcm8060847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6616885/
https://www.ncbi.nlm.nih.gov/pubmed/31200579
http://dx.doi.org/10.3390/jcm8060847

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