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Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells

The zinc finger transcription factor Snail is a known effector of epithelial-to-mesenchymal transition (EMT), a process that underlies the enhanced invasiveness and chemoresistance of common to cancerous cells. Induction of Snail-driven EMT has also been shown to drive a range of pro-survival metabo...

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Detalles Bibliográficos
Autores principales: Liu, Menghan, Hancock, Sarah E., Sultani, Ghazal, Wilkins, Brendan P., Ding, Eileen, Osborne, Brenna, Quek, Lake-Ee, Turner, Nigel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617272/
https://www.ncbi.nlm.nih.gov/pubmed/31181802
http://dx.doi.org/10.3390/jcm8060822