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Snail-Overexpression Induces Epithelial-mesenchymal Transition and Metabolic Reprogramming in Human Pancreatic Ductal Adenocarcinoma and Non-tumorigenic Ductal Cells
The zinc finger transcription factor Snail is a known effector of epithelial-to-mesenchymal transition (EMT), a process that underlies the enhanced invasiveness and chemoresistance of common to cancerous cells. Induction of Snail-driven EMT has also been shown to drive a range of pro-survival metabo...
Autores principales: | Liu, Menghan, Hancock, Sarah E., Sultani, Ghazal, Wilkins, Brendan P., Ding, Eileen, Osborne, Brenna, Quek, Lake-Ee, Turner, Nigel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617272/ https://www.ncbi.nlm.nih.gov/pubmed/31181802 http://dx.doi.org/10.3390/jcm8060822 |
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