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Loss of XBP1 Leads to Early-Onset Retinal Neurodegeneration in a Mouse Model of Type I Diabetes

Retinal neuronal injury and degeneration is one of the primary manifestations of diabetic retinopathy, a leading cause of vision loss in working age adults. In pathological conditions, including diabetes and some physiological conditions such as aging, protein homeostasis can become disrupted, leadi...

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Detalles Bibliográficos
Autores principales: McLaughlin, Todd, Siddiqi, Manhal, Wang, Joshua J., Zhang, Sarah X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617367/
https://www.ncbi.nlm.nih.gov/pubmed/31242599
http://dx.doi.org/10.3390/jcm8060906