Monoallelic expression and epigenetic inheritance sustained by a Trypanosoma brucei variant surface glycoprotein exclusion complex

The largest gene families in eukaryotes are subject to allelic exclusion, but mechanisms underpinning single allele selection and inheritance remain unclear. Here, we describe a protein complex sustaining variant surface glycoprotein (VSG) allelic exclusion and antigenic variation in Trypanosoma bru...

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Detalles Bibliográficos
Autores principales: Faria, Joana, Glover, Lucy, Hutchinson, Sebastian, Boehm, Cordula, Field, Mark C., Horn, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617441/
https://www.ncbi.nlm.nih.gov/pubmed/31289266
http://dx.doi.org/10.1038/s41467-019-10823-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617441/
https://www.ncbi.nlm.nih.gov/pubmed/31289266
http://dx.doi.org/10.1038/s41467-019-10823-8

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