Dual Kit/Aur Inhibitors as Chemosensitizing Agents for the Treatment of Melanoma: Design, Synthesis, Docking Studies and Functional Investigation

Melanoma is the most serious form of skin cancer but its medication is still far from being safe and thoroughly effective. The search of novel therapeutic approaches represents therefore a health emergency to push through eagerly. In this study, we describe a novel class of dual c-Kit/Aur inhibitors...

Descripción completa

Detalles Bibliográficos
Autores principales: Quattrini, Luca, Coviello, Vito, Sartini, Stefania, Di Desidero, Teresa, Orlandi, Paola, Ke, Yi-Yu, Liu, Kai-Lun, Hsieh, Hsing-Pang, Bocci, Guido, La Motta, Concettina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617451/
https://www.ncbi.nlm.nih.gov/pubmed/31289333
http://dx.doi.org/10.1038/s41598-019-46287-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617451/
https://www.ncbi.nlm.nih.gov/pubmed/31289333
http://dx.doi.org/10.1038/s41598-019-46287-5

Ejemplares similares