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Chronic exposure to high fat diet triggers myelin disruption and interleukin-33 upregulation in hypothalamus

BACKGROUND: Hypothalamic inflammation including astrogliosis and microglia activation occurs after intake of high fat diet (HFD) in rodent models or in obese individuals. However, the effect of chronic HFD feeding on oligodendrocytes (OLGs), a myelin-producing glial population in the central nervous...

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Detalles Bibliográficos
Autores principales: Huang, Hui-Ting, Tsai, Sheng-Feng, Wu, Hung-Tsung, Huang, Hsin-Ying, Hsieh, Han-Hsueh, Kuo, Yu-Ming, Chen, Po-See, Yang, Chung-Shi, Tzeng, Shun-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617565/
https://www.ncbi.nlm.nih.gov/pubmed/31291887
http://dx.doi.org/10.1186/s12868-019-0516-6