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The protective effect and mechanism of the FXR agonist obeticholic acid via targeting gut microbiota in non-alcoholic fatty liver disease

Background: It is reported that various diseases such as non-alcoholic fatty liver disease (NAFLD) are associated with imbalance of microbiome. And FXR has been well investigated in liver diseases. Purpose: The objective of this study was to identify the role of farnesoid X receptor agonist obeticho...

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Detalles Bibliográficos
Autores principales: Zhang, Dan-Ying, Zhu, Lin, Liu, Hai-Ning, Tseng, Yu-Jen, Weng, Shu-Qiang, Liu, Tao-Tao, Dong, Ling, Shen, Xi-Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617567/
https://www.ncbi.nlm.nih.gov/pubmed/31308634
http://dx.doi.org/10.2147/DDDT.S207277