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APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression

BACKGROUND: Canonical WNT signalling plays a critical role in the regulation of ovarian development; mis-regulation of this key pathway in the adult ovary is associated with subfertility and tumourigenesis. The roles of Adenomatous polyposis coli 2 (APC2), a little-studied WNT signalling pathway reg...

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Detalles Bibliográficos
Autores principales: Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R., Smalley, Matthew J., Clarke, Alan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617595/
https://www.ncbi.nlm.nih.gov/pubmed/31291912
http://dx.doi.org/10.1186/s12885-019-5867-y