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APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression
BACKGROUND: Canonical WNT signalling plays a critical role in the regulation of ovarian development; mis-regulation of this key pathway in the adult ovary is associated with subfertility and tumourigenesis. The roles of Adenomatous polyposis coli 2 (APC2), a little-studied WNT signalling pathway reg...
Autores principales: | Mohamed, Noha-Ehssan, Hay, Trevor, Reed, Karen R., Smalley, Matthew J., Clarke, Alan R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617595/ https://www.ncbi.nlm.nih.gov/pubmed/31291912 http://dx.doi.org/10.1186/s12885-019-5867-y |
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