Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux

BACKGROUND: Gliomas are the most common primary tumors in central nervous system. Despite advances in diagnosis and therapy, the prognosis of glioma remains gloomy. Autophagy is a cellular catabolic process that degrades proteins and damaged organelles, which is implicated in tumorigenesis and tumor...

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Detalles Bibliográficos
Autores principales: Wen, Zhi-peng, Zeng, Wen-jing, Chen, Yan-hong, Li, He, Wang, Jie-ya, Cheng, Quan, Yu, Jing, Zhou, Hong-hao, Liu, Zheng-zheng, Xiao, Jian, Chen, Xiao-ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617611/
https://www.ncbi.nlm.nih.gov/pubmed/31291988
http://dx.doi.org/10.1186/s13046-019-1287-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617611/
https://www.ncbi.nlm.nih.gov/pubmed/31291988
http://dx.doi.org/10.1186/s13046-019-1287-8

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