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Knockdown ATG4C inhibits gliomas progression and promotes temozolomide chemosensitivity by suppressing autophagic flux
BACKGROUND: Gliomas are the most common primary tumors in central nervous system. Despite advances in diagnosis and therapy, the prognosis of glioma remains gloomy. Autophagy is a cellular catabolic process that degrades proteins and damaged organelles, which is implicated in tumorigenesis and tumor...
Autores principales: | Wen, Zhi-peng, Zeng, Wen-jing, Chen, Yan-hong, Li, He, Wang, Jie-ya, Cheng, Quan, Yu, Jing, Zhou, Hong-hao, Liu, Zheng-zheng, Xiao, Jian, Chen, Xiao-ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617611/ https://www.ncbi.nlm.nih.gov/pubmed/31291988 http://dx.doi.org/10.1186/s13046-019-1287-8 |
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