Involvement of epigenetic modification of TERT promoter in response to all-trans retinoic acid in ovarian cancer cell lines

BACKGROUND: All-trans retinoic acid (ATRA) is currently being used to treat hematological malignancies, given the ability to inhibit cell proliferation. This effect seems to be related to epigenetic changes of the TERT (Telomerase Reverse Transcriptase) promoter. When hypomethylated, ATRA-inducible...

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Detalles Bibliográficos
Autores principales: Losi, Lorena, Lauriola, Angela, Tazzioli, Erica, Gozzi, Gaia, Scurani, Letizia, D’Arca, Domenico, Benhattar, Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617683/
https://www.ncbi.nlm.nih.gov/pubmed/31291979
http://dx.doi.org/10.1186/s13048-019-0536-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617683/
https://www.ncbi.nlm.nih.gov/pubmed/31291979
http://dx.doi.org/10.1186/s13048-019-0536-y

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