The formyl peptide fMLF primes platelet activation and augments thrombus formation

ESSENTIALS: The role of formyl peptide receptor 1 (FPR1) and its ligand, fMLF, in the regulation of platelet function, hemostasis, and thrombosis is largely unknown. Fpr1‐deficient mice and selective inhibitors for FPR1 were used to investigate the function of fMLF and FPR1 in platelets. N‐formyl‐me...

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Detalles Bibliográficos
Autores principales: Salamah, Maryam F., Ravishankar, Divyashree, Vaiyapuri, Rajendran, Moraes, Leonardo A., Patel, Ketan, Perretti, Mauro, Gibbins, Jonathan M., Vaiyapuri, Sakthivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617722/
https://www.ncbi.nlm.nih.gov/pubmed/31033193
http://dx.doi.org/10.1111/jth.14466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617722/
https://www.ncbi.nlm.nih.gov/pubmed/31033193
http://dx.doi.org/10.1111/jth.14466

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