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The formyl peptide fMLF primes platelet activation and augments thrombus formation
ESSENTIALS: The role of formyl peptide receptor 1 (FPR1) and its ligand, fMLF, in the regulation of platelet function, hemostasis, and thrombosis is largely unknown. Fpr1‐deficient mice and selective inhibitors for FPR1 were used to investigate the function of fMLF and FPR1 in platelets. N‐formyl‐me...
Autores principales: | Salamah, Maryam F., Ravishankar, Divyashree, Vaiyapuri, Rajendran, Moraes, Leonardo A., Patel, Ketan, Perretti, Mauro, Gibbins, Jonathan M., Vaiyapuri, Sakthivel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617722/ https://www.ncbi.nlm.nih.gov/pubmed/31033193 http://dx.doi.org/10.1111/jth.14466 |
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