Cargando…

The formyl peptide fMLF primes platelet activation and augments thrombus formation

ESSENTIALS: The role of formyl peptide receptor 1 (FPR1) and its ligand, fMLF, in the regulation of platelet function, hemostasis, and thrombosis is largely unknown. Fpr1‐deficient mice and selective inhibitors for FPR1 were used to investigate the function of fMLF and FPR1 in platelets. N‐formyl‐me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Salamah, Maryam F., Ravishankar, Divyashree, Vaiyapuri, Rajendran, Moraes, Leonardo A., Patel, Ketan, Perretti, Mauro, Gibbins, Jonathan M., Vaiyapuri, Sakthivel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	PLATELETS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617722/ https://www.ncbi.nlm.nih.gov/pubmed/31033193 http://dx.doi.org/10.1111/jth.14466

Ejemplares similares

Ruthenium-conjugated chrysin analogues modulate platelet activity, thrombus formation and haemostasis with enhanced efficacy
por: Ravishankar, Divyashree, et al.
Publicado: (2017)

The Antimicrobial Cathelicidin CRAMP Augments Platelet Activation during Psoriasis in Mice
por: Salamah, Maryam F., et al.
Publicado: (2020)

Impact of specific functional groups in flavonoids on the modulation of platelet activation
por: Ravishankar, Divyashree, et al.
Publicado: (2018)

1,8-Cineole Affects Agonists-Induced Platelet Activation, Thrombus Formation and Haemostasis
por: Alatawi, Kahdr A., et al.
Publicado: (2021)

Effect of ultrapure lipopolysaccharides derived from diverse bacterial species on the modulation of platelet activation
por: Vallance, Thomas M., et al.
Publicado: (2019)

Non-genomic effects of PPARγ ligands: inhibition of GPVI-stimulated platelet activation
por: Moraes, L A, et al.
Publicado: (2010)

The Urokinase/Urokinase Receptor System in Mast Cells: Effects of its Functional Interaction with fMLF Receptors
por: Rossi, Francesca Wanda, et al.
Publicado: (2016)

The platelet-surface thiol isomerase enzyme ERp57 modulates platelet function
por: Holbrook, L-M, et al.
Publicado: (2012)

A gain‐of‐function filamin A mutation in mouse platelets induces thrombus instability
por: Adam, Frédéric, et al.
Publicado: (2022)

Platelet endothelial cell adhesion molecule-1 regulates collagen-stimulated platelet function by modulating the association of phosphatidylinositol 3-kinase with Grb-2-associated binding protein-1 and linker for activation of T cells
por: Moraes, L A, et al.
Publicado: (2010)

Platelet collagen receptor Glycoprotein VI‐dimer recognizes fibrinogen and fibrin through their D‐domains, contributing to platelet adhesion and activation during thrombus formation
por: Induruwa, I., et al.
Publicado: (2018)

Impacts of Commonly Used Edible Plants on the Modulation of Platelet Function
por: Albadawi, Dina A. I., et al.
Publicado: (2022)

PPARγ agonists negatively regulate αIIbβ3 integrin outside‐in signaling and platelet function through up‐regulation of protein kinase A activity
por: Unsworth, A. J., et al.
Publicado: (2017)

The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis
por: Sasikumar, P., et al.
Publicado: (2018)

A humanized monoclonal antibody that inhibits platelet‐surface ERp72 reveals a role for ERp72 in thrombosis
por: Holbrook, L.‐M., et al.
Publicado: (2018)

Synthetic Flavonoids as Novel Modulators of Platelet Function and Thrombosis
por: Vallance, Thomas M., et al.
Publicado: (2019)

Anti‐GPVI nanobody blocks collagen‐ and atherosclerotic plaque–induced GPVI clustering, signaling, and thrombus formation
por: Jooss, Natalie J., et al.
Publicado: (2022)

K(Ca)3.1-Dependent Hyperpolarization Enhances Intracellular Ca(2+) Signaling Induced by fMLF in Differentiated U937 Cells
por: Penna, Antonello, et al.
Publicado: (2015)

Mean platelet size related to glycoprotein-specific autoantibodies and platelet-associated IgG
por: JAVELA, K, et al.
Publicado: (2007)

Activation mechanism dependent surface exposure of cellular factor XIII on activated platelets and platelet microparticles
por: Somodi, Laura, et al.
Publicado: (2022)

SMIFH2 inhibition of platelets demonstrates a critical role for formin proteins in platelet cytoskeletal dynamics
por: Green, Hannah L. H., et al.
Publicado: (2020)

Multimerin 1 supports platelet function in vivo and binds to specific GPAGPOGPX motifs in fibrillar collagens that enhance platelet adhesion
por: Leatherdale, Alexander, et al.
Publicado: (2020)

Manipulating megakaryocytes to manufacture platelets ex vivo
por: Karagiannis, P, et al.
Publicado: (2015)

Amplification of human platelet activation by surface pannexin-1 channels
por: Taylor, K A, et al.
Publicado: (2014)

Modified platelet deposition on matrix metalloproteinase 13 digested collagen I
por: Howes, J.‐M., et al.
Publicado: (2015)

Circulating primers enhance platelet function and induce resistance to antiplatelet therapy
por: Blair, T A, et al.
Publicado: (2015)

Anti‐platelet antibodies in childhood immune thrombocytopenia: Prevalence and prognostic implications
por: Schmidt, David E., et al.
Publicado: (2020)

Eugenol prevents fMLF-induced superoxide anion production in human neutrophils by inhibiting ERK1/2 signaling pathway and p47phox phosphorylation
por: Chniguir, Amina, et al.
Publicado: (2019)

Differential roles for the adapters Gads and LAT in platelet activation by GPVI and CLEC-2
por: HUGHES, C E, et al.
Publicado: (2008)

Super‐resolution microscopy as a potential approach to diagnosis of platelet granule disorders
por: Westmoreland, D., et al.
Publicado: (2016)

Phagocytosis by endothelial cells inhibits procoagulant activity of platelets of essential thrombocythemia in vitro
por: Ji, Shuting, et al.
Publicado: (2019)

Removal of platelets from blood plasma to improve the quality of extracellular vesicle research
por: Bettin, Britta, et al.
Publicado: (2022)

Diagnostic utility of the ISTH bleeding assessment tool in patients with suspected platelet function disorders
por: Adler, Marcel, et al.
Publicado: (2019)

Flow cytometric mepacrine fluorescence can be used for the exclusion of platelet dense granule deficiency
por: van Asten, Ivar, et al.
Publicado: (2019)

Platelet count and indices as postpartum hemorrhage risk factors: a retrospective cohort study
por: van Dijk, Wobke E. M., et al.
Publicado: (2021)

Measurement of procoagulant platelets provides mechanistic insight and diagnostic potential in heparin‐induced thrombocytopenia
por: Lee, Christine S. M., et al.
Publicado: (2022)

Maintaining flippase activity in procoagulant platelets is a novel approach to reducing thrombin generation
por: Millington‐Burgess, Sarah L., et al.
Publicado: (2022)

Repurposing Cancer Drugs Batimastat and Marimastat to Inhibit the Activity of a Group I Metalloprotease from the Venom of the Western Diamondback Rattlesnake, Crotalus atrox
por: Layfield, Harry J., et al.
Publicado: (2020)

CLEC‐2‐dependent activation of mouse platelets is weakly inhibited by cAMP but not by cGMP
por: Borgognone, A., et al.
Publicado: (2014)

Novel assay demonstrates that coronary artery disease patients have heightened procoagulant platelet response
por: Pasalic, L., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_f2vikmi71sr9khu1kllial8d0f