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Cell type-specific epigenetic links to schizophrenia risk in the brain

BACKGROUND: The importance of cell type-specific epigenetic variation of non-coding regions in neuropsychiatric disorders is increasingly appreciated, yet data from disease brains are conspicuously lacking. We generate cell type-specific whole-genome methylomes (N = 95) and transcriptomes (N = 89) f...

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Detalles Bibliográficos
Autores principales: Mendizabal, Isabel, Berto, Stefano, Usui, Noriyoshi, Toriumi, Kazuya, Chatterjee, Paramita, Douglas, Connor, Huh, Iksoo, Jeong, Hyeonsoo, Layman, Thomas, Tamminga, Carol A., Preuss, Todd M., Konopka, Genevieve, Yi, Soojin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617737/
https://www.ncbi.nlm.nih.gov/pubmed/31288836
http://dx.doi.org/10.1186/s13059-019-1747-7