Germline variation in BRCA1/2 is highly ethnic‐specific: Evidence from over 30,000 Chinese hereditary breast and ovarian cancer patients

BRCA1 and BRCA2 play essential roles in maintaining the genome stability. Pathogenic germline mutations in these two genes disrupt their function, lead to genome instability and increase the risk of developing breast and ovarian cancers. BRCA mutations have been extensively screened in Caucasian pop...

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Detalles Bibliográficos
Autores principales: Bhaskaran, Shanmuga Priya, Chandratre, Khyati, Gupta, Hemant, Zhang, Li, Wang, Xiaoyu, Cui, Jian, Kim, Yeong C., Sinha, Siddharth, Jiang, Luhan, Lu, Boya, Wu, Xiaobing, Qin, Zixin, Huang, Teng, Wang, San Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Cancer Genetics and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617753/
https://www.ncbi.nlm.nih.gov/pubmed/30702160
http://dx.doi.org/10.1002/ijc.32176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617753/
https://www.ncbi.nlm.nih.gov/pubmed/30702160
http://dx.doi.org/10.1002/ijc.32176

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