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Apolipoprotein E associated with reconstituted high‐density lipoprotein‐like particles is protected from aggregation
Apolipoprotein E (APOE) genotype determines Alzheimer's disease (AD) susceptibility, with the APOE ε4 allele being an established risk factor for late‐onset AD. The ApoE lipidation status has been reported to impact amyloid‐beta (Aβ) peptide metabolism. The details of how lipidation affects Apo...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617784/ https://www.ncbi.nlm.nih.gov/pubmed/31058310 http://dx.doi.org/10.1002/1873-3468.13428 |