MIC‐MAC: An automated pipeline for high‐throughput characterization and classification of three‐dimensional microglia morphologies in mouse and human postmortem brain samples

The phenotypic changes of microglia in brain diseases are particularly diverse and their role in disease progression, beneficial, or detrimental, is still elusive. High‐throughput molecular approaches such as single‐cell RNA‐sequencing can now resolve the high heterogeneity in microglia population f...

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Detalles Bibliográficos
Autores principales: Salamanca, Luis, Mechawar, Naguib, Murai, Keith K., Balling, Rudi, Bouvier, David S., Skupin, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617786/
https://www.ncbi.nlm.nih.gov/pubmed/30983036
http://dx.doi.org/10.1002/glia.23623

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617786/
https://www.ncbi.nlm.nih.gov/pubmed/30983036
http://dx.doi.org/10.1002/glia.23623

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