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MIC‐MAC: An automated pipeline for high‐throughput characterization and classification of three‐dimensional microglia morphologies in mouse and human postmortem brain samples
The phenotypic changes of microglia in brain diseases are particularly diverse and their role in disease progression, beneficial, or detrimental, is still elusive. High‐throughput molecular approaches such as single‐cell RNA‐sequencing can now resolve the high heterogeneity in microglia population f...
Autores principales: | Salamanca, Luis, Mechawar, Naguib, Murai, Keith K., Balling, Rudi, Bouvier, David S., Skupin, Alexander |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617786/ https://www.ncbi.nlm.nih.gov/pubmed/30983036 http://dx.doi.org/10.1002/glia.23623 |
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