Heterozygosity mapping for human dominant trait variants

Homozygosity mapping is a well‐known technique to identify runs of homozygous variants that are likely to harbor genes responsible for autosomal recessive disease, but a comparable method for autosomal dominant traits has been lacking. We developed an approach to map dominant disease genes based on...

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Detalles Bibliográficos
Autores principales: Imai‐Okazaki, Atsuko, Li, Yi, Horpaopan, Sukanya, Riazalhosseini, Yasser, Garshasbi, Masoud, Mosse, Yael P., Zhang, Di, Schrauwen, Isabelle, Sharma, Aarushi, Fann, Cathy S. J., Leal, Suzanne M., Lathrop, Mark, Ott, Jurg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Methods
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617796/
https://www.ncbi.nlm.nih.gov/pubmed/31018026
http://dx.doi.org/10.1002/humu.23765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617796/
https://www.ncbi.nlm.nih.gov/pubmed/31018026
http://dx.doi.org/10.1002/humu.23765

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