Self-microemulsifying drug delivery system (SMEDDS) for improved oral delivery and photostability of methotrexate

Purpose: The objective of this study was to exploit a novel methotrexate (MTX)-loaded solid self-microemulsifying drug delivery system (SMEDDS) with enhanced bioavailability and photostability. Materials and methods: The optimized liquid SMEDDS was composed of castor oil, Tween(®) 80, and Plurol(®)...

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Detalles Bibliográficos
Autores principales: Kim, Dong Shik, Cho, Jung Hyun, Park, Jong Hyuck, Kim, Jung Suk, Song, Eon Soo, Kwon, Jaewook, Giri, Bhupendra Raj, Jin, Sung Giu, Kim, Kyeong Soo, Choi, Han-Gon, Kim, Dong Wuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617838/
https://www.ncbi.nlm.nih.gov/pubmed/31308665
http://dx.doi.org/10.2147/IJN.S211014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6617838/
https://www.ncbi.nlm.nih.gov/pubmed/31308665
http://dx.doi.org/10.2147/IJN.S211014

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